ACTIVEApril 2026
NAION Vision Loss Lawsuits Centralized in Federal MDL
Defendants: Novo Nordisk, Eli Lilly
Drugs: Semaglutide (Ozempic, Wegovy), Tirzepatide (Mounjaro, Zepbound)
Allegations: Plaintiffs allege the drugs caused non-arteritic anterior ischemic optic neuropathy (NAION) — sudden vision loss — and that manufacturers knew the risk from trial data but failed to warn adequately.
Key details: A 2024 Harvard study found semaglutide users had a significantly elevated NAION risk. The FDA expanded its investigation in early 2026. Plaintiffs report partial or complete vision loss in one or both eyes.
Next steps
An MDL consolidation hearing is scheduled. Bellwether trial selection is expected in late 2026.
ACTIVEMarch 2026
Ozempic Gallbladder Injury Lawsuits — Cholecystectomy Claims
Defendants: Novo Nordisk
Drugs: Semaglutide (Ozempic, Wegovy)
Allegations: Suits allege semaglutide caused acute gallbladder disease, gallstones, and cholecystitis requiring emergency removal, and that Novo downplayed the risk despite trial data.
Key details: FDA adverse-event reports show thousands of gallbladder complaints. A 2022 study found higher gallbladder event rates in GLP-1 users versus placebo; many plaintiffs had no prior gallbladder issues.
Next steps
Cases are being consolidated with the gastroparesis MDL. Bellwether selection is anticipated in late 2026.
ACTIVEFebruary 2026
Gastroparesis / Stomach Paralysis Mass Tort Litigation
Defendants: Novo Nordisk, Eli Lilly
Drugs: Semaglutide, Tirzepatide, Liraglutide
Allegations: Hundreds allege the drugs caused severe gastroparesis, cyclic vomiting syndrome, and intestinal obstruction, with some symptoms persisting months or years after stopping.
Key details: The litigation argues manufacturers failed to adequately warn about the severity and duration of GI effects. Several cases involve hospitalization for bowel obstructions.
Next steps
Discovery is ongoing; expert witness reports are due mid-2026. Settlement talks have not begun.
ACTIVEJanuary 2026
Novo Nordisk Class Action — Pricing & Supply Manipulation
Defendants: Novo Nordisk A/S
Drugs: Ozempic, Wegovy
Allegations: Plaintiffs allege Novo artificially maintained the semaglutide shortage to keep prices high and block compounding competition, while manipulating FDA supply data.
Key details: The class includes patients who paid inflated prices and compounding pharmacies. The suit seeks damages for overcharges and injunctive relief.
Next steps
A class certification hearing is scheduled for Q2 2026. Novo has filed a motion to dismiss.
ACTIVEJanuary 2026
Novo Nordisk Securities Class Action — Failure to Disclose Safety Risks
Defendants: Novo Nordisk A/S
Drugs: Ozempic, Wegovy
Allegations: Shareholders allege Novo failed to disclose known safety risks (vision loss, severe gastroparesis), inflating the stock price that later fell when the signals became public.
Key details: The complaint cites internal documents suggesting awareness of elevated NAION risk before public disclosure and alleges risks were downplayed to investors.
Next steps
A lead plaintiff was appointed and an amended complaint filed. A motion to dismiss is pending.
SETTLEDNovember 2025
FTC Settlement — NextMed Pays $150K for Deceptive GLP-1 Claims
Defendants: NextMed (telehealth provider)
Drugs: Semaglutide, Tirzepatide
Allegations: The FTC alleged deceptive advertising: guaranteed weight-loss claims, misleading before/after photos, unsubstantiated testimonials, and undisclosed endorser connections.
Key details: The provider agreed to pay $150,000 and accept a permanent injunction against future deceptive claims.
Next steps
The settlement is finalized. NextMed is subject to compliance monitoring for five years.
ACTIVEDecember 2025
Compounding Pharmacy Fraud — Multi-State Criminal Investigation
Defendants: Multiple compounding pharmacies (names sealed)
Drugs: Compounded Semaglutide, Compounded Tirzepatide
Allegations: Federal prosecutors are pursuing wire fraud, introduction of adulterated drugs, and conspiracy to defraud patients.
Key details: Investigators uncovered vials labeled as semaglutide with little or no active ingredient, undisclosed substances, and forged certificates of analysis from unlicensed pharmacies.
Next steps
Grand jury proceedings are underway in three federal districts. Indictments are expected in Q2 2026.
ACTIVEOctober 2025
Pancreatitis Wrongful Death Lawsuits
Defendants: Novo Nordisk, Eli Lilly
Drugs: Semaglutide, Tirzepatide
Allegations: Families of patients who died from acute pancreatitis allegedly caused by GLP-1s claim the manufacturers gave inadequate severity warnings.
Key details: The suits cite patients who developed necrotizing pancreatitis within weeks of starting, leading to multi-organ failure and death.
Next steps
Individual cases are proceeding in state courts. No consolidation has been sought at this time.
ACTIVESeptember 2025
Eli Lilly Patent Enforcement — Compounding Pharmacy Injunctions
Defendants: Multiple compounding pharmacies
Drugs: Compounded Tirzepatide
Allegations: Eli Lilly brought patent-infringement suits against compounders making tirzepatide copies, arguing tirzepatide was never in shortage so there was no legal basis to compound it.
Key details: Lilly obtained temporary restraining orders against several pharmacies and is seeking permanent injunctions, citing both safety risk and IP infringement.
Next steps
Preliminary injunction hearings are ongoing. Several pharmacies stopped tirzepatide compounding voluntarily.