ShedRx or SkinnyRx: Which GLP-1 Program Fits You? (2026)

Both ShedRx and SkinnyRx can get you started on a GLP-1 from home — the question is which one suits the way you want to be cared for. We’ve put them side by side on price, medications, coverage, and the support you can count on, so you can pick with confidence instead of a shrug.

Our pick: SkinnyRx

For most people, SkinnyRx (9/10) just nudges ahead of ShedRx (8.9/10). That doesn’t make ShedRx the wrong choice, though — it may actually be the better fit if what you’re after is the widest needle-free menu

ShedRx

8.9$195/mo

Skip the needle if you'd like — drops, lozenges, and tablets, in all 50 states.

Pros

Needle-free options: sublingual drops, lozenges, and tablets
Available in all 50 states
Health coaching included with your plan

Cons

Lowest prices require a 12-month plan
Brand-name options need a membership add-on

Best for: The widest needle-free menu

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SkinnyRx

Our pick of the two

9$199/mo

Compounded or brand-name, in shots, drops, or tablets — whatever fits you best.

Pros

Choose injections, sublingual drops, or daily tablets
Compounded and brand-name GLP-1s both available
Overnight pharmacy shipping

Cons

Best price needs a 12-month bundle (single months cost more)
Brand-name options cost noticeably more

Best for: Brand-name and compounded under one roof

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The two, side by side

Feature	ShedRx	SkinnyRx
Monthly price	$195	$199
Rating	8.9 / 10	9 / 10
Medication type	Brand & Compounded	Brand & Compounded
Insurance	Not Accepted	Not Accepted
States available	All 50	All 50
Consultation fee	Included	Included
Shipping	Free	Overnight
Cancel anytime	Yes	Yes

Prices shown are starting rates without insurance. Seed data — please verify before relying on it.

Common questions about these two programs

On our scoring, ShedRx sits at 8.9/10 and SkinnyRx at 9/10 — but the honest answer is that it comes down to what you need most. ShedRx tends to shine for the widest needle-free menu, while SkinnyRx is the stronger pick for brand-name and compounded under one roof

ShedRx starts at $195/month and SkinnyRx at $199/month. Semaglutide from ~$175/mo (12-mo); needle-free lozenges from ~$199/mo. Semaglutide from $199/mo (12-mo bundle); tirzepatide from ~$299/mo. Those are starting figures, so check each program directly before you budget around them.

ShedRx is cash-pay only, and SkinnyRx is cash-pay only. If a program is cash-pay, you may still be able to put FSA or HSA dollars toward it.

Through ShedRx you can get Compounded Semaglutide, Compounded Tirzepatide, Oral drops & lozenges, Brand Wegovy, Brand Zepbound. SkinnyRx offers Compounded Semaglutide, Compounded Tirzepatide, Brand-name GLP-1s. Your prescriber decides which one is right for you from what each program stocks.

ShedRx serves all 50 states, and SkinnyRx serves all 50 states. State coverage can change, so do a quick check before you sign up.

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