Barrett’s Research

ShedRx or Yucca Health: Which GLP-1 Program Fits You? (2026)

Both ShedRx and Yucca Health can get you started on a GLP-1 from home — the question is which one suits the way you want to be cared for. We’ve put them side by side on price, medications, coverage, and the support you can count on, so you can pick with confidence instead of a shrug.

Our pick: Yucca Health

For most people, Yucca Health (9.3/10) just nudges ahead of ShedRx (8.9/10). That doesn’t make ShedRx the wrong choice, though — it may actually be the better fit if what you’re after is the widest needle-free menu

ShedRx

8.9$195/mo

Skip the needle if you'd like — drops, lozenges, and tablets, in all 50 states.

Pros

  • Needle-free options: sublingual drops, lozenges, and tablets
  • Available in all 50 states
  • Health coaching included with your plan

Cons

  • Lowest prices require a 12-month plan
  • Brand-name options need a membership add-on

Best for: The widest needle-free menu

Yucca Health

Our pick of the two
9.3$129/mo

A fast, friendly path to semaglutide or tirzepatide — no membership, no runaround.

Pros

  • No membership fee — the price you see is the price you pay
  • Free 2-day shipping on your medication
  • 100% online intake with US-licensed prescribers

Cons

  • Compounded medication only — no brand-name pens
  • Cash-pay, so you can't bill it to insurance

Best for: A fast start with no membership fee

The two, side by side

FeatureShedRxYucca Health
Monthly price$195$129
Rating8.9 / 109.3 / 10
Medication typeBrand & CompoundedCompounded
InsuranceNot AcceptedNot Accepted
States availableAll 50All 50
Consultation feeIncludedIncluded
ShippingFreeFree 2-day
Cancel anytimeYesYes

Prices shown are starting rates without insurance. Seed data — please verify before relying on it.

Common questions about these two programs

On our scoring, ShedRx sits at 8.9/10 and Yucca Health at 9.3/10 — but the honest answer is that it comes down to what you need most. ShedRx tends to shine for the widest needle-free menu, while Yucca Health is the stronger pick for a fast start with no membership fee
ShedRx starts at $195/month and Yucca Health at $129/month. Semaglutide from ~$175/mo (12-mo); needle-free lozenges from ~$199/mo. Semaglutide from $129/mo, tirzepatide from $146/mo. No membership fee. Those are starting figures, so check each program directly before you budget around them.
ShedRx is cash-pay only, and Yucca Health is cash-pay only. If a program is cash-pay, you may still be able to put FSA or HSA dollars toward it.
Through ShedRx you can get Compounded Semaglutide, Compounded Tirzepatide, Oral drops & lozenges, Brand Wegovy, Brand Zepbound. Yucca Health offers Compounded Semaglutide, Compounded Tirzepatide. Your prescriber decides which one is right for you from what each program stocks.
ShedRx serves all 50 states, and Yucca Health serves all 50 states. State coverage can change, so do a quick check before you sign up.
2-minute match quiz

Not sure which program is the right fit?

Answer six quick questions and we'll point you to the programs that suit your budget, your insurance, and how you want to be cared for.